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On average, you can get Celebrex oral capsule for 180 dollars for 10 capsules of 200mg. What side effects may I notice from Celebrex? You develop dizziness, depression, or confusion Answers. Celebrex (celecoxib) relieves pain and inflammation by blocking COX-2 enzymes, which are responsible for the synthesis of prostaglandins (prostaglandins are released during inflammation and elevate body temperature and make nerve endings more sensitive to pain transmission). The peak blood levels occur within three hours ( Pharmacogenetics and Genomics, April, 2012) For people with osteoarthritis pain, the recommended dose is either 100 mg twice a day or 200 mg once a day. This drug is used for both rheumatoid arthritis and osteoarthritis. It is available in the US and other countries, but making the drug more powerful is still in progress. 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